Course Description

A. COVER PAGE

Date of Submission (Please include Month, Day and Year)
1. Course Title BIOLOGY	9. Subject Area History/Social Science English Mathematics x Laboratory Science Language other than English Visual & Performing Arts Intro Advanced College Prep Elective
2. Transcript Title(s) / Abbreviation(s) BIO
3. Transcript Course Code(s) / Number(s) 6210, Bio HPA 6212, SDAIE 6214, AA 6217, MAOS 6219
4. School Monterey/Marina/Seaside High Schools
5. District Monterey Peninsula Unified
6. City Monterey	10. Grade Level(s) for which this course is designed X 9 X 10 X 11 X 12
7. School / District Web Site www.mpusd.k12.ca.us	11. Seeking “Honors” Distinction? Yes X No
8. School Course List Contact Name: Kari Yeater Title/Position: Assistant Superintendent (C and I) Phone: 831-645-1212 Ext.: E-mail: kyeater@mpusd.k12.ca.us	12. Unit Value 0.5 (half year or semester equivalent) X 1.0 (one year equivalent) 2.0 (two year equivalent) Other: _______________________________
13. Is this an Internet-based course? Yes X No If “Yes”, who is the provider? UCCP PASS/Cyber High Other __
14. Complete outlines are not needed for courses that were previously approved by UC. If course was previously approved, indicate in which category it falls. A course reinstated after removal within 3 years. Year removed from list? ___________ Same course title? Yes No If no, previous course title? ___________________________________________________________ An identical course approved at another school in same district. Which school? _________________ Same course title? Yes No If no, course title at other school? ______________________________________________________ Year-long VPA course replacing two approved successive semester courses in the same discipline Approved Advanced Placement (AP) or International Baccalaureate (IB) course Approved UC College Prep (UCCP) Online course Approved CDE Agricultural Education course Approved P.A.S.S./Cyber High course Approved ROP/C course. Name of ROP/C? ______________________________________________ Approved A.V.I.D. course Approved C.A.R.T. course Approved Project Lead the Way course Other. Explain: _____________________________________________________________________
15. Is this course modeled after an UC-approved course from another school outside your district? Yes X No If so, which school(s)? ______________________________________________________________________ Course title at other school __________________________________________________________________
16. Pre-Requisites Concurrent enrollment or completion of Algebra I
17. Co-Requisites None
18. Is this course a resubmission? X Yes No If yes, date(s) of previous submission? _________________________________________________________ Title of previous submission? ________________________________________________________________
19. Brief Course Description Biology I is a standards-based, college preparatory laboratory science course. The course starts with a review of chemistry and energy, building upon the students’ study of the eighth grade content standards for “Chemistry of Living Systems”. The instruction expands in depth upon the seventh-grade “Focus on Life Sciences” content standards and reinforces prior knowledge of scientific inquiry and methods. After the review of biological chemistry, the principles of cellular biology, including respiration and photosynthesis are taught. This is followed by instruction in molecular and Medelian genetics. Population genetics and evolution follow naturally from the study of genetics and lead to a discussion of diversity of form and physiology. The teaching culminates with ecology, a subject that draws on each of the preceding topics.

B. COURSE CONTENT

20. Course Goals and/or Major Student Outcomes:

1. Students will demonstrate the ability to use the scientific method to solve problems, use tools of scientific measurement, and gain familiarity with techniques common to scientific experimentation.

2. Students will demonstrate an understanding of the fundamental principles of chemistry as they relate to the biological sciences.

3. Students will demonstrate an understanding of the basic principles of cell biology.

4. Students will demonstrate a detailed understanding of the increasingly important role that genetics, molecular biology and biotechnology play in the biological sciences. These areas constitute a major portion of the course.

5. Students will demonstrate knowledge of the theory of evolution by natural selection and its central role in biology.

6. Students will demonstrate an ecological understanding of the biosphere.

7. Students will demonstrate an understanding of the structure and function of organ systems and the mechanisms that organisms use to combat disease.

21. Course Objectives:

a) Students will know that the fundamental life processes of plants and animals depend on a variety of chemical reactions that occur in specialized areas of the organism’s cells.

b) Students will know that mutation and sexual reproduction lead to genetic variation in a population.

c) Students will know that a multicellular organism develops from a single zygote, and that its phenotype depends on its genotype, which is established at fertilization.

d) Students will know that genes are a set of instructions encoded in the DNA sequence of each organism that specify the sequence of amino acids in proteins characteristic of that organism.

e) Students will know that the genetic composition of cells can be altered by incorporation of exogenous DNA into the cells.

f) Students will know that stability in an ecosystem is a balance between competing effects.

g) Students will know that the frequency of an allele in a gene pool of a population depends on many factors and may be stable or unstable over time.

h) Students will know that evolution is the result of genetic changes that occur in constantly changing environments.

i) Students will know that as a result of the coordinated structures and functions of organ systems, the internal environment of the human body remains relatively stable (homeostatic) despite changes in the outside environment.

j) Students will know that organisms have a variety of mechanisms to combat disease.

k) Students will know that scientific progress is made by asking meaningful questions and conducting careful investigations.

22. Course Outline

1. Scientific Method/Techniques

• Use of metric system
• Use of microscope
• Use of chemical indicators
• Quantitative/Qualitative Measurement
• Hypothesis testing and theory formation

2. Biological Chemistry

• Atomic Structure
• Chemical Bonds
• Molecules
• Compounds
• Monomers
• Polymers
• Acids and Bases
• pH
• Carbohydrates
• Lipids
• Proteins
• Nucleic Acids (DNA & RNA)
• Enzymes

3. Cell Biology

• Cell Theory
• Viruses
• Prokaryotes
• Eukaryotes (Plant and Animal)
• Cell Membrane
• Osmosis and chemiosmotic gradients
• Cell Energy (photosynthesis and cellular respiration)
• Organelle Structure and Function
• Nucleus (structure and function)

4. Genetics (Meiosis and Fertilization)

• Mitosis
• Meiosis
• Genetic Variation in Population
• Mutations
• Random Segregation
• Fertilization
• Role of Chromosomes in Sex Determination

5. Genetics (Mendelian Genetics)

• Genetics Problems using Punnett Squares (autosomal, sex-linked, simple dominance, codominance, incomplete dominance and multiple alleles)
• Pedigrees
• Karyotypes
• Gene Mapping

6. Genetics (Molecular Biology)

• General structure of nucleic acids and proteins
• DNA replication (semiconservative)
• Base pairing rules
• Transcription and translation
• Sequencing DNA
• Mutations
• Gene expression

7. Genetics (Biotechnology)

• Genetic engineering
• Basic DNA technology (including gel electrophoresis)
• Recombinant DNA
• Plasmids
• Bacterial transformation

8. Evolution (Population Genetics)

• Natural Selection
• Allele frequencies
• Mutation and genetic variation
• Hardy-Weinberg equilibrium

9. Evolution (Speciation)

• Genetic drift
• Reproductive and geographic isolation
• Fossil evidence
• Comparative embryology
• DNA and protein sequence comparisons
• Episodic speciation
• Mass extinctions
• Cladograms
• Molecular clocks

10. Ecology

• Biogeochemical cycles
• Energy pyramids and food webs
• Stability and change in ecosystems
• Fluctuations in populations in an ecosystem
• Human influences and other impacts on ecosystems
• Organismal adaptations to the environment

11. Physiology (Homeostasis)

• Complementary activity of major body systems
• Nervous system and sensory organs
• Cellular and molecular basis of muscle contraction
• Digestive and excretory processes
• Function of endocrine system in maintaining homeostasis

12. Physiology (Infection and Immunity)

• Primary defenses against bacterial and viral infections
• Nonspecific defenses against infection
• Role of antibodies in response to infection
• Vaccination
• Compromised immune systems
• Roles of phagocytes, B-lymphocytes, and T-lymphocytes

23. Texts & Supplemental Instructional Materials

Text: Miller, Kenneth R. and Levine, Joseph. Biology. Prentice Hall. 2002

The following list of lab equipment, chemicals, and expendables is representative of the typical needs of an instructor following this course description. It is not exclusive, may be modified as necessary, and instructors may require additional materials.

Biology Lab Equipment:

beakers (various sizes)	glass microscope slides	Microcentrifuges	spot plates
coverslips	graduated cylinders	microscopes (compound and dissecting)	stirring rods
culture tubes	hand lenses	petri dishes	Stopwatches
dissecting tool kits	hot plates	pH paper	test tube racks
dissecting trays	incubators	pH probes	test tubes (various sizes)
electronic balances	jars	Pipetters	thermometers (alcohol)
electrophoresis power supplies	lab aprons	Pipettes	thermometers (probes)
erlenmeyer flasks	lams	razor blades	Triple-beam balances
eye droppers	magnetic stirrers	rubber stoppers	tubing (glass and plastic)
gel electrophoresis chambers	metric rulers	safety goggles	UV lamps
		Scissors	water baths

Chemical Supplies and Solutions:

Acetone	Glucose	Methylene blue	Potassium permanganate
Benedict's solution	Hydrochloric acid	Nitric acid	Sodium Hydroxide
Bleach	Hydrogen peroxide	Petroleum ether	Starch
Bromthymol blue